(CNN) — In a first-of-its-kind study, researchers have developed a blood test for Alzheimer’s disease that predicts with astonishing accuracy whether a healthy person will develop the disease.
Though much work still needs to be done, it is hoped the test will someday be available in doctors’ offices, since the only methods for predicting Alzheimer’s right now, such as PET scans and spinal taps, are expensive, impractical, often unreliable and sometimes risky.
"This is a potential game-changer," said Dr. Howard Federoff, senior author of the report and a neurologist at Georgetown University Medical Center. "My level of enthusiasm is very high."
The study was published in Nature Medicine.
'We were surprised'
In the beginning, the researchers knew they wanted to find a blood test to detect Alzheimer’s but didn’t know what specifically to look for. Should they examine patients’ DNA? Their RNA? Or should they look for the byproducts of DNA and RNA, such as fats and proteins?
They decided to start with fats, since it was the easiest and least expensive. They drew blood from hundreds of healthy people over age 70 living near Rochester, New York, and Irvine, California. Five years later, 28 of the seniors had developed Alzheimer’s disease or the mild cognitive problems that usually precede it.
Scouring more than 100 fats, or lipids, for what might set this group apart, they found that these 28 seniors had low levels of 10 particular lipids, compared with healthy seniors.
To confirm their findings, the researchers then looked at the blood of 54 other patients who had Alzheimer’s or mild cognitive impairment. This group also had low levels of the lipids.
Overall, the blood test predicted who would get Alzheimer’s or mild cognitive impairment with over 90% accuracy.
"We were surprised," said Mark Mapstone, a neuropsychologist at the University of Rochester Medical Center and lead author of the study. "But it turns out that it appears we were looking in the right place."
For 12 years now, the strident dyspeptic voice of the “Redneck” population has hemmed and hawed and hacked and gagged on Republican right-wing conservative swill until even they can no longer accept the thunderations of some turkey neck Republican politician’s revoltingly immoral pledging allegiance to the one-percent corportacracy and out right racism. This is a blow to the Republicans now forced to witness those they thought so ignorant and incompetent re-evaluating the black president they have tried so desperately to undermine. Moral to this revelation: everyone finally reaches the limit of self-imposed poverty for irrelevant beliefs resulting in recognizing the gluttony for power stolen by the few with the protection of those elected to safeguard the public’s best interest who have sold out to big money.
I was born a JFK Liberal and have watched America become a shoddy, obsolescent, unemployed and impoverished nation by the Republican Party of so-called right-wing conservatives immoral hypocrites who have made “equal justice under the law” a vicious mockery bereft of reason and decency.
Can you explain how God created traditional marriage 2000 years ago? What you call “traditional marriage” was simply the civil laws of the Greeks and Romans. The Jewish “traditions” of having multiple wives were “illegal” like the Mormon and Muslim traditions today. As a TV character said, if you could reason with religious people, there would be no religious people. There will always be a subset of people who refuse to accept some aspect of reality because it frightens them, and they will cling to some superstition or another for comfort. No amount of evidence will satisfy these folks. They’ll only go deeper into their delusions to try to escape the obvious.
Americans have gotten far stupider in the last 40 years since Republicans starting attacking public education and promoting ‘home schooling” which allows far too many kids to be indoctrinated with religious garbage at the expense of science and true literacy.
Objectivists are more properly Mammonists, who differ from Satanists, in that the latter understand that Satan is not real; while Mammonists, whose idol is money, do not know that the same is true about their own object of worship.
“We live in a society exquisitely dependent on science and technology, in which hardly anyone knows anything about science and technology.”—Carl Sagan, Why We Need To Understand Science (via givncvrlos)